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用于光学相干层析成像OCT的MEMS扫描镜
来源:https://www.mdpi.com/2304-6732/8/1/6 | 作者:频谱科学 | 发布时间: 2023-04-06 | 798 次浏览 | 分享到:

MEMS Scanning Mirrors for Optical Coherence Tomography

用于光学相干层析成像的MEMS扫描镜

1
International Center for Translational Eye Research, Institute of Physical Chemistry, Polish Academy of Sciences, Skierniewicka 10A, 01-230 Warsaw, Poland
2
FEMTO-ST Institute (UMR CNRS 6714/UBFC), 15B Avenue des Montboucons, 25030 Besançon, France
*
Author to whom correspondence should be addressed.
Photonics 20218(1), 6; https://doi.org/10.3390/photonics8010006

Abstract

This contribution presents an overview of advances in scanning micromirrors based on MEMS (Micro-electro-mechanical systems) technologies to achieve beam scanning for OCT (Optical Coherence Tomography). The use of MEMS scanners for miniaturized OCT probes requires appropriate optical architectures. Their design involves a suitable actuation mechanism and an adapted imaging scheme in terms of achievable scan range, scan speed, low power consumption, and acceptable size of the OCT probe. The electrostatic, electromagnetic, and electrothermal actuation techniques are discussed here as well as the requirements that drive the design and fabrication of functional OCT probes. Each actuation mechanism is illustrated by examples of miniature OCT probes demonstrating the effectiveness of in vivo bioimaging. Finally, the design issues are discussed to permit users to select an OCT scanner that is adapted to their specific imaging needs.

这篇文章概述了基于MEMS(微机电系统)技术扫描微镜以实现OCT(光学相干断层扫描)光束扫描的进展。将MEMS扫描仪用于小型化OCT探针需要适当的光学架构。他们的设计涉及合适的致动机构和合适的成像方案,包括可实现的扫描范围、扫描速度、低功耗和OCT探头的可接受尺寸。本文讨论了静电、电磁和电热驱动技术,以及驱动功能性OCT探针设计和制造的要求。微型OCT探针的例子说明了每种致动机制,证明了体内生物成像的有效性。最后,讨论了设计问题,以允许用户选择适合其特定成像需求的OCT扫描仪。

1. Introduction

Micro-electro-mechanical systems (MEMS) technology enables the building of microoptical scanners that are well suited for low cost manufacturability and scalability as the MEMS processes emanate from the mature semiconductor microfabrication industry [1]. For a long time, the potential of MEMS to steer or direct light has been well demonstrated in the field of free-space optical systems [2]. In the 80s and early 90s, telecommunications became the market driver for the optical applications of MEMS, pushing the development of scanning micromirror systems for optical switches and network ports [3]. More recently, many types of MEMS scanning mirrors have been developed, covering a wide range of applications from micrometer-scale array-type components to large scanners for high-resolution imaging [4]. Thus, numerous optical imaging techniques such as confocal microscopy [5,6], multiphoton microscopy [7,8], and Optical Coherence Tomography (OCT) [9,10,11] have become important diagnostic tools in biomedicine, particularly offering a platform for endoscopic imaging. These MEMS scanners successfully replaced the bulky and high power consuming galvanometer scanners, providing compact, low cost, and low power consumption solutions for high speed beam steering. Further, 2D MEMS mirrors that scan in two axes are a pertinent alternative to the large galvano-scanners [12].
The MEMS scanner’s performances are closely linked to the size of the selected actuator, carrying the micromirror and the force developed by this actuator. Figure 1 represents a summary of scanning micromirror applications, including the corresponding actuation mechanisms and main microfabrication technologies [13]. At the scale level, going from 1 mm to 1 cm, the MEMS technology combined with fiber optics enables miniature scanning components to be embedded inside the endoscopic imaging probes operating at high speed and high resonance frequency. The MEMS scanners are relatively easily integrated and adapted for low cost fabrication and low power consumption. The miniaturization performances and subsequent advances in standardized micromachining technologies have also offered numerous low cost and disposable OCT probes for the medical industry. Originally adopted by the ophthalmic community [14,15,16], OCT has been used to image internal organs, such as the gastrointestinal tract [17], and in the diagnosis of skin pathologies [18,19]. This strong interest for clinical applications pushed several companies to develop endoscopic OCT systems [20]. Examples of commercial products are the clinical endoscope and catheter-based systems from the NvisionVLE® Imaging System (South Jordan, Utah, USA) [21], the intravascular OCT imaging systems from OPTIS™ (St. Jude Medical Inc., St. Paul, MN, USA) [22], Santec’s (Komaki, Japan) swept-source OCT systems [23], Thorlabs (Newton, NJ, USA) OCT scanners [24], as well as Mirrorcle (Richmond, CA, USA) microscanners [25].

Photonics 08 00006 g001

Figure 1. Applications, actuation mechanisms, and fabrication technologies for scanning micromirrors.
In this paper, we will demonstrate that for OCT imaging applications, the performance of the MEMS scanner is often limited by optics and intrinsic characteristics of actuation mechanisms. Here, optics require a small focused spot and dynamic focusing, imposing severe restrictions on scanning lens performances, while the actuation needs a high scanning speed, a low power consumption, a precise control of motion linearity, and reduced cross-axis coupling, which may distort the scanning patterns [26,27]. The group of OCT probes to be discussed in this paper do maintain such opto-mechanical performances, using different actuation mechanisms. Our wish is to demonstrate that the breakthrough of compactness is obtained when MEMS dual-axis beam-steering micromirrors [28] are used to achieve scanning 3D OCT probes. In the case of endoscopic applications, they are small enough to be included into a standard endoscope channel, with an inner diameter of 2.8 mm. Further, 2D scanning motion can derive from electrostatic, electromagnetic, electrothermal, or piezoelectric actuation, providing the scanning mirrors for light beam steering, operating at high speed and fully controlled by non-resonant or resonant regimes. However, we intentionally excluded from the present study piezoelectric actuation and we consider only the three other actuation mechanisms for MEMS scanning mirrors that are the most widely used in OCT applications.

2. Requirements for MEMS Microscanners

From the user point of view, performances of scanning micromirrors are defined by the maximum scan angle, the number of resolvable spots which represents the scan resolution, the resonance frequency, as well as the surface quality vs. the smoothness and flatness of micromirrors.
The number of resolvable spots N of a scanning mirror is defined as a function of optical scan angle  and beam divergence , as shown in Figure 2:
==,
where D is the mirror diameter, a represents the aperture shape factor (a = 1 in the case of a square aperture and 1.22 for a circular aperture) and  is the illumination wavelength.


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